SPRX is trading at $48.05, a -1.52% change, as a surge in the 10-year Treasury yield pressures growth-stock valuations. - The 10-year yield reached approximately 5.14%, its highest level since 2007. - Strong September business activity pushed the S&P Global composite PMI to a 62-month high of 58.4, reinforcing expectations the Federal Reserve may keep rates elevated. - Nasdaq weakness and higher oil prices are adding to risk-off sentiment.