Quantum BioPharma is trading up 5.41% in pre-market at $4.06 on September 28; no new company announcement dated September 28 surfaced in the search. - The shares closed at $3.85 on September 25. - FDA approved the IND application for Lucid-MS on September 25, clearing the way for Phase 2 testing; no source explicitly links the news to the pre-market gain. - Broad market conditions are weaker, so a market-wide explanation is not supported by the supplied context.