SeaStar Medical is trading 5.29% down at $3.35 in pre-market, based on the provided price, following a $3.54 close on September 18, 2026; no clear catalyst was identified.

  • No new company-specific announcement or clearly identified overnight catalyst was found for September 21.
  • The latest official update was a September 10 presentation announcement; recent conference materials discussed adult-trial enrollment and future commercialization plans.
  • Broader U.S. markets were higher pre-market, so the decline does not clearly track overall market sentiment.