Harmony Biosciences is trading at $33.00, down 8.41%, amid Wakix patent-litigation uncertainty, the clearest recent company-specific overhang.

  • Closing arguments in the case against AET Pharma took place earlier this week; no ruling was reported.
  • Mizuho saw no clear winner or loser, but said investors viewed the arguments as unfavorable and attributed the prior-session decline to that view.
  • October 22 volume was about 2.9 million shares, over three times average. No announcement explained the October 23 pre-market move; third-quarter results are scheduled for November 4.