Cardio Diagnostics Holdings is trading 6.3% up in pre-market at $2.02, compared with the September 30 close of $1.90, with no clear company-specific catalyst identified. - The company’s official press-release page provided no details identifying a fresh catalyst, and available news results showed no October 1 announcement. - Major U.S. index futures were modestly higher, but none exceeded the stated 0.5% threshold, leaving broader market sentiment without a clear explanation for the move.